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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 6.36
Human Site: S398 Identified Species: 10.77
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S398 G S S E A A G S P E W G G R P
Chimpanzee Pan troglodytes XP_510208 819 88957 S540 G S S E A A G S P E W G G R P
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 L333 R P P A L G S L L D P L P T A
Dog Lupus familis XP_548005 637 70371 S371 S R P P A L E S L L G P L P T
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 D397 D G S E A A G D P D G G S R P
Rat Rattus norvegicus NP_001100231 686 74096 D407 G G S E A A E D A D G G S R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 G403 E D G D C K N G N E A P V R P
Frog Xenopus laevis NP_001088063 660 73751 V390 L A D T S K R V Y E H T V K P
Zebra Danio Brachydanio rerio NP_956183 693 76806 D397 R D Q G G K K D L D G R K N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 G396 D V K K S E P G G L V A G I E
Honey Bee Apis mellifera XP_623775 648 73504 A382 Q N S E S S N A N N R L I I G
Nematode Worm Caenorhab. elegans NP_495526 759 84015 S396 E D P C T S N S L E K Y D K Y
Sea Urchin Strong. purpuratus XP_794011 768 83924 D465 E K T L P S G D V I D T L L G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 Q330 L T Q V L G E Q E L S S K E V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 0 13.3 N.A. 60 53.3 N.A. N.A. 20 13.3 0 N.A. 6.6 13.3 13.3 6.6
P-Site Similarity: 100 100 6.6 13.3 N.A. 66.6 60 N.A. N.A. 26.6 33.3 6.6 N.A. 20 40 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 36 29 0 8 8 0 8 8 0 0 8 % A
% Cys: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 22 8 8 0 0 0 29 0 29 8 0 8 0 0 % D
% Glu: 22 0 0 36 0 8 22 0 8 36 0 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 22 15 8 8 8 15 29 15 8 0 29 29 22 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 8 15 0 % I
% Lys: 0 8 8 8 0 22 8 0 0 0 8 0 15 15 0 % K
% Leu: 15 0 0 8 15 8 0 8 29 22 0 15 15 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 22 0 15 8 0 0 0 8 0 % N
% Pro: 0 8 22 8 8 0 8 0 22 0 8 15 8 8 43 % P
% Gln: 8 0 15 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 15 8 0 0 0 0 8 0 0 0 8 8 0 36 0 % R
% Ser: 8 15 36 0 22 22 8 29 0 0 8 8 15 0 0 % S
% Thr: 0 8 8 8 8 0 0 0 0 0 0 15 0 8 15 % T
% Val: 0 8 0 8 0 0 0 8 8 0 8 0 15 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _